Amino Creative | Portfolio Categories Devices + Instrumentation
Amino Creative, LLC. Specializing in conceptualization, communication, and clarity for science and medicine. Located in Boston, Massachusetts, United States
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Structural Heart Disease Intervention and New Onset Conduction Disturbances

A series of illustrations for a research article published in Structural Heart reviewing the anatomy of the heart’s conduction system in the proximity of structural heart disease defects. The illustrations demonstrate how the anatomy in individuals with certain atrial and ventricular septal defects has clinical significance: undergoing percutaneous interventions can contribute to risk of developing inadvertent conduction disturbances.

These illustrations explore a number of anatomical considerations and serve as a lead-in to the discussion of emerging strategies to address complications caused by procedures in this population.

Left atrial appendage occlusion and peri-device leaks

A series of illustrations for a research article published in Structural Heart investigating the clinical significance and diagnostic assessment of peri-device leaks (PDL) after interventions targeting the left atrial appendage (LAA), for the reduction of cardioembolic risk in individuals with nonvalvular atrial fibrillation.

These illustrations explore a few of the anatomical considerations and possible pathological mechanisms concerning PDL after LAA occlusion or closure procedures. These types of patient-to-patient variations and challenges in device planning, placement, and outcomes demonstrate an opportunity to develop better modalities to identify and quantitate PDL.

A Novel Approach to Ablation Therapy

A series of illustrations was created for a medical device company investigating a novel ablation approach using a high-power, low-current radiofrequency ablation catheter (Sphere-9/Affera, Inc).

One key challenge in creating focal lesions is to do so with adequate coverage and depth, yet minimal-to-no injury to surrounding anatomy beyond the epicardium. In these selected illustrations (published in 2 research articles), several moments in cross-section were selected to compare the capabilities of a conventional ablation catheter and that of a novel expandable, lattice-structured catheter, in both thick and thin tissue applications.

Dynamic semi-realistic rendering is combined with clear color differences, measurements, and labeling to help the reader compare the researchers’ experimental findings regarding the dimensions of resistive and conductive heating—aspects that have different tissue injury profiles, and which create distinct, lasting lesion patterns.

Barkagan M, et al. Circ Arrhythm Electrophysiol. 2019.12(4):e007879.

Kitamura T, et al. J Cardiovasc Electrophysiol. 2019.30(9):1644-1651.

CPT Professional

Images created for the AMA (Current Procedural Terminology) CPT Assistant Newsletter and the CPT Professional code book. Each image or set of images accompanies explanations of new or updated codes for reporting specific techniques and procedures. Topics range from general esophagectomy techniques, to differences in approach to minimally-invasive glaucoma surgery, to placement of a non-tunneling peripherally-inserted central catheter in a pediatric patient.

The Secret of Life (MIT Biology 7.012)

Several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.

Total artificial heart implantation

Illustration for the June 2018 AMA (Current Procedural Terminology) CPT Assistant Newsletter. Accompanies an explanation of the new Cardiovascular codes 33927-33929 to report artificial heart system procedures.

Wisdom Wrap

A series of illustrations created for the Wisdom Wrap® product packaging insert.

This hot/cold gel pack therapy product has a unique variety of applications; these illustrations describe the steps to achieve optimum use.

Harris-Galante hip implants

A series of illustrations for The Harris Orthopaedic Laboratory @ The Mass General by William H. Harris, MD.

The figures depict examples of hip implant designs developed by John Charnley, MD, including approaches to: articular surface replacement, femoral head/neck replacement, wear durability, and stabilization/retention.

Additional illustrations show design changes by Dr Harris and his colleague Dr Jorge Galante, including approaches to improving and optimizing: fixation and integration for both cementless and cement femoral head/neck and cup, replaceable cup liners, and individual customization and standardized, interchangeable components.

Layer-by-layer assembly featured image

Technology-driven layer-by-layer assembly of nanofilms

A series of illustrations accompanying an in-depth review article published in Science, examining the interdisciplinary environment that has produced novel layer-by-layer (LBL) assembly technology. The 5 main LBL assembly approaches are discussed as it applies to producing different resulting material properties. The authors also focus on future scalability and harnessing the strengths of different types of LBL assembly for use in advancing scientific research and practical use in biomedicine, optics, membranes, among other various applications.