Series of illustrations created for a new video case series, NEJM Double Takes. This video highlights the effects of climate change on health through an illustrative patient case. Viewers are guided through the clinical presentation, differential diagnosis, laboratory studies, and treatment, culminating in the final diagnosis.
This video is one in a series of educational videos produced for a bio-nutrient company that focuses on sustainable plant nutrition. It introduces the basics of soil health, and is used to highlight key mechanistic advantages of the company’s products and formulations in the areas of soil chemistry, soil biology, and plant physiology. The video is utilized in an educational lecture/presentational setting for sales representatives, customers, and distributors.
Images created for the 2021 Lasker-DeBakey Clinical Medical Research Award honoring two scientists—Katalin Karikó (BioNTech) and Drew Weissman (University of Pennsylvania) and their discovery of a therapeutic technology based on the modification of messenger RNA. The images celebrate how their breakthrough was applied in the development of a highly effective Covid-19 vaccine strategy.
An illustration accompanying an in-depth review article published in ACS Central Science. The article examines how tumorigenesis affects blood-brain barrier (BBB) integrity, and how nanomaterial properties affect uptake and retention in brain tissue, with the goal of creating more patient-specific, predictive treatment approaches.
This illustration demonstrates a progression of changes in the tumor microenvironment of a mouse model in the study. Shown are relative degree of BBB breakdown, large and small nanoparticle permeability across the BBB, and tumor-associated vascularization during early, middle, and late stages of tumor development.
A series of illustrations created for the Food Allergies Science Initiative (FASI) at the Broad Institute, as part of their public awareness and funding campaigns.
The images provide an overview of the anatomical and cellular basis of food ‘quality control,’ involving detection by taste, smell, and specialized ‘nutrient-sensing’ and ‘toxin-sensing’ cells, joined with neural and immune pathway regulation.
Current FASI research focuses on unravelling this complex system, elucidating mechanisms of inflammatory and immune responses to particular foods, and making advances in diagnosis, prevention, and treatment.
This illustration accompanies an article published in Nature Nanotechnology. It highlights the importance of improving one of many barriers to progress in the multidisciplinary field of biological application of nanotechnology (‘bio-nano’)—that of standards of experiment reporting in scientific publication. The article proposes components in 3 main categories: material and biological characterization, and experimental protocol details.
A series of illustration accompanying an in-depth review article published in Advanced Materials, examining the structure and functional aspects of the blood brain barrier (BBB). The article focuses on the role of nanomaterials and nanoparticles as part of evolving noninvasive therapeutic strategies designed to either bypass or cross the BBB. Many strategies of interest have the potential to exploit existing endogenous pathways—natural mechanisms of cellular transport in the central nervous system—and could be combined with novel techniques in localization and targeting.
An image created for the Centers of Disease Control and Prevention (CDC) depicting the movement of the West Nile virus through its vector: a female Culex sp. mosquito.
Several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
Illustration series for Redox Bio-Nutrients, a company that focuses on sustainable plant nutrition.
We helped to establish a brand-specific appearance to explain the basics of plant biology and soil dynamics, and to highlight key mechanistic advantages of Redox plant nutrition products and formulations that boost plant growth, quality, and yield.